Nezperce High School offers a variety of academically orientated extra curricular activities. Students have the opportunity to join various clubs including FFA (Future Farmers of America), BPA (Business Professionals of America) and FCCLA (Family Career and Community Leaders of America). Other activities include Knowledge Bowl team, JETS (Mathematics team), INL(Engineering team), National Honor Society and Knowledgemaster.

Members of the FFA need to be enrolled in an agriculture class. Dues are necessary to pay both district and local membership. Members are involved in judging contests and may attend the State Conference at Twin Falls. Nezperce students have also attended the national conferences at Kansas City and Louisville.

All high school students are eligible to join BPA (Business Professionals of  America). Membership dues are $15.00 which are used to pay for national, regional, and state dues. Members must help with fundraising and participate at regional competition. Regional winners may compete at the state competition held annually at Boise State University. 

FCCLA (Family, Career and Community Leaders of America) is open to all high school students; dues are $15.00 (state and national dues). Members must assist with fundraisers and participate in a community service project. Members that qualify may attend the State Conference held in Boise each year.

This club is open to any high school girl. The club has fundraisers and sponsors the Sadie Hawkins Dance and the Mother-Daughter Tea.

Competition is held once a month on a Monday night. Each school is allowed to field up to three teams of six students each. Juniors and Seniors and students with previous knowledge bowl experience will be given first preference.

This is a computerized competition held twice during the school year. Participants are chosen on the basis of interest, willingness to practice, ability to work together in a group and areas of expertise. Students in grades 10 - 12 compose the high school team and students in grades 7 - 9 compose the junior high team.

This contest is a buzzer format. The regional tournament is held during the spring semester, usually on the campus of one of the colleges in northern Idaho. The winning team for the State of Idaho will earn a trip to the National Science Bowl in Washington DC. Team members are chosen by interest, willingness to practice, and expertise in the areas of math and science.

This is a group contest based on engineering principals. The state and national contests are held during the spring semester, usually at the University of Idaho. Eight students compose a team. Members are chosen by interest and expertise in the areas of math and science.